| Category | ORIGINAL_ARTICLE |
|---|---|
| Authors | Abhishek Singhai, Anand Baharani |
| Abstract | Background: Moringa oleifera (M. oleifera) is the most widely cultivated species of the genus Moringa. An antidiabetic property is included among the medicinal benefits of M. oleifera. Aim: This study was designed to evaluate the efficacy of the M. oleifera leaf extract in lowering the blood sugar levels for two groups categorized as being normal and hyperglycemic. Methods: Total 50 subjects were derived into two groups based on fasting blood sugar levels. They were classified either as normal or hyperglycaemic. Normal fasting blood sugar levels were considered as those with levels of 70-110 mg/dl, while hyperglycaemia was if blood sugar levels more than 110 mg/dl. Of the 50 subjects, 25 were normal and 25 were hyperglycaemic. Fasting blood sugar estimation was done from venous blood . Each subject was asked to swallow commercially available M. oleifera leaf extract in the dose of 500 mg along with regular breakfast . Two hours after taking the M. oleifera capsule, the blood sugar levels were measured again. Statistical significance of the change in blood sugar readings was determined using paired-samples t-test. Results: Mean (SD) FBS was 83.84 (2.4) mg/dl among normal subjects. Mean (SD) FBS was 140.28 (3.1) mg/dl among hyperglycemic subjects. Overall, there was a mean change of +14.12 for the normal group and -17.96 for the hyperglycemia group. Both values were statistically significant. (p<0.001). Conclusion: Our study shows that M.oleifera leaf extract has blood sugar lowering effects in hyperglycemic individuals, while in normal subjects blood sugar increased after breakfast as a normal phenomenon . KEYWORDS: Moringa oleifera, antidiabetic, hyperglycemia, polyphenols. |
| Year | 2016 |
| Month | April |
| Volume | 5 |
| Issue | 2 |
| Published On | 12 Apr 2016 |
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